
	The ICD-9-CM codes used in the economic impact analysis by musculoskeletal diseases fall into the two categories of base codes and expansive codes.
	Conditions included in the base musculoskeletal disease rubric include spine conditions, arthritis and joint pain, the category that includes osteoporosis (other diseases of bone and cartilage), injuries, and an inclusive “other” category for the remaining conditions. Conditions selected for the cost analysis presented are based on condition topics included in this site. Data are reported primarily for base case ICD-9-CM codes, or those codes for which musculoskeletal disease is the principal cause of the condition rather than a consequence of another major health condition (eg, bone cancer metastases from another primary cancer site).
	Estimates are also provided for a more expansive list of codes of musculoskeletal-related diseases that include conditions for which musculoskeletal diseases are either the primary and secondary cause of the condition. This more expansive list of conditions yields a vastly larger prevalence estimate than the base case list. However, it is reasonable to assume the cost of musculoskeletal diseases probably exceeds the conservative estimates presented here. For example, a person with bone metastases would incur costs to treat the bone manifestation, even though the cancer, not the bone condition, is the primary etiology.
	 ICD-9-CM codes included in each subcategory for the base and expansive conditions are listed in subsections.
	Spine        
	    Special Symptoms or Syndromes, NEC : 307
	    Migraine: 346
	    Trigeminal Nerve Disorders : 350
	    Nerve Root and Plexus Disorders : 353
	    Dentofacial Anomalies, Including Malocclusion : 524
	    Pain and Other Symptoms Associated with Female Genital Organs : 625
	    Menopausal and Postmenopausal Disorders : 627
	    General Symptoms : 780
	    Symptoms Involving Skin and Other Integumentary Tissue : 782
	    Symptoms Involving Head and Neck : 784
	    Symptoms Involving Respiratory System and Other Chest Symptoms :    786
	    Symptoms Involving Digestive System : 787
	    Other Symptoms Involving Abdomen and Pelvis : 789
	    Injury to Other Cranial Nerve(s) : 951
	    Injury to Nerve Roots and Spinal Plexus : 953
	Arthritis and Joint Pain        
	    Gonococcal Infections : 098
	    Other Venereal Diseases : 099
	    Other and Unspecified Infectious and Parasitic Diseases : 136
	    Other and Unspecified Disorders of Metabolism : 277
	    Purpura and Other Hemorrhagic Conditions : 287
	    Other Paralytic Syndromes : 344
	    Mononeuritis of Upper Limb and Mononeuritis Multiplex : 354
	    Inflammatory and Toxic Neuropathy : 357
	    Other and Ill-defined Cerebrovascular Disease : 437
	    Other Peripheral Vascular Disease : 443
	    Polyarteritis Nodosa and Allied Conditions : 446
	    Other Disorders of Arteries and Arterioles : 447
	    Psoriasis and Similar Disorders : 696
	Osteoporosis        
	    Other Disorders of Bone and Cartilage : 733        
	Musculoskeletal Injuries        
	    Open Wound of Neck : 874
	    Open Wound of Other and Unspecified Sites, Except Limbs : 879
	    Contusion of Trunk : 922
	    Contusion of Upper Limb : 923
	    Contusion of Lower Limb and of Other and Unspecified Sites : 924
	    Crushing Injury of Trunk : 926
	Other Musculoskeletal Conditions        
	    Other Salmonella Infections : 3
	    Rat-bite Fever : 26
	    Meningococcal Infection : 36
	    Rubella : 56
	    Other Arthropod-borne Diseases : 88
	    Early Syphilis, Symptomatic : 91
	    Other Forms of Late Syphilis, with Symptoms : 95
	    Yaws : 102
	    Late Effects of Tuberculosis : 137
	    Malignant Neoplasm of Other and Ill-defined Sites : 195
	    Secondary Malignant Neoplasm of Other Specified Sites : 198
	    Other Malignant Neoplasms of Lymphoid and Histiocytic Tissue : 202
	    Multiple Myeloma and Immunoproliferative Neoplasms : 203
	    Other Benign Neoplasm of Connective and Other Soft Tissue : 215
	    Neoplasm of Uncertain Behavior of Other and Unspecified Sites and Tissues : 238
	    Neoplasms of Unspecified Nature : 239
	    Disorders of Parathyroid Gland : 252
	    Disorders of Lipoid Metabolism : 272
	    Disorders of Mineral Metabolism :  275
	    Hereditary Hemolytic Anemias : 282
	    Organic Sleep Disorders : 327
	    Mononeuritis of Lower Limb and Unspecified Site : 355
	    Peritonitis and Retroperitoneal Infections : 567
	    Other Cellulitis and Abscess : 682
	    Other and Unspecified Congenital Anomalies : 759
	    Late Effects of Injuries to Skin and Subcutaneous Tissues : 906
	    Certain Early Complications of Trauma : 958
	    Complications Peculiar to Certain Specified Procedures : 996
	    Personal History of Other Diseases : V13
	    Organ or Tissue Replaced By Transplant : V42
	    Organ or Tissue Replaced By Other Means : V43
	    Other Postprocedural States : V45
	    Problems with Head, Neck, and Trunk : V48
	    Fitting and Adjustment of Other Device : V53
	    Convalescence and Palliative Care : V66
	    Follow-up Examination : V67
	    Special Screening Examination for Bacterial and Spirochetal Diseases : V74
	Spine        
	    Special Symptoms or Syndromes, NEC : 307
	    Migraine : 346
	    Trigeminal Nerve Disorders : 350
	    Nerve Root and Plexus Disorders : 353
	    Dentofacial Anomalies, Including Malocclusion : 524
	    Pain and Other Symptoms Associated with Female Genital Organs : 625
	    Menopausal and Postmenopausal Disorders : 627
	    General Symptoms : 780
	    Symptoms Involving Skin and Other Integumentary Tissue : 782
	    Symptoms Involving Head and Neck : 784
	    Symptoms Involving Respiratory System and Other Chest Symptoms : 786
	    Symptoms Involving Digestive System : 787
	    Other Symptoms Involving Abdomen and Pelvis : 789
	    Injury to Other Cranial Nerve(s) : 951
	    Injury to Nerve Roots and Spinal Plexus : 953
	Arthritis and Joint Pain        
	    Gonococcal Infections : 098
	    Other Venereal Diseases : 099
	    Other and Unspecified Infectious and Parasitic Diseases : 136
	    Other and Unspecified Disorders of Metabolism : 277
	    Purpura and Other Hemorrhagic Conditions : 287
	    Other Paralytic Syndromes : 344
	    Mononeuritis of Upper Limb and Mononeuritis Multiplex : 354
	    Inflammatory and Toxic Neuropathy : 357
	    Other and Ill-defined Cerebrovascular Disease : 437
	    Other Peripheral Vascular Disease : 443
	    Polyarteritis Nodosa and Allied Conditions : 446
	    Other Disorders of Arteries and Arterioles : 447
	    Psoriasis and Similar Disorders : 696
	Osteoporosis        
	    Due to small sample sizes, no additional codes were included in the expansive analysis.       
	Musculoskeletal Injuries        
	    Open Wound of Neck : 874
	    Open Wound of Other and Unspecified Sites, Except Limbs : 879
	    Contusion of Trunk : 922
	    Contusion of Upper Limb : 923
	    Contusion of Lower Limb and of Other and Unspecified Sites : 924
	    Crushing Injury of Trunk : 926
	Other Musculoskeletal Conditions        
	    Other Salmonella Infections : 3
	    Rat-bite Fever : 26
	    Meningococcal Infection : 36
	    Rubella : 56
	    Other Arthropod-borne Diseases : 88
	    Early Syphilis, Symptomatic : 91
	    Other Forms of Late Syphilis, with Symptoms : 95
	    Yaws : 102
	    Late Effects of Tuberculosis :  137
	    Malignant Neoplasm of Other and Ill-defined Sites : 195
	    Secondary Malignant Neoplasm of Other Specified Sites : 198
	    Other Malignant Neoplasms of Lymphoid and Histiocytic Tissue : 202
	    Multiple Myeloma and Immunoproliferative Neoplasms : 203
	    Other Benign Neoplasm of Connective and Other Soft Tissue : 215
	    Neoplasm of Uncertain Behavior of Other and Unspecified Sites and Tissues : 238
	    Neoplasms of Unspecified Nature : 239
	    Disorders of Parathyroid Gland : 252
	    Disorders of Lipoid Metabolism : 272
	    Disorders of Mineral Metabolism : 275
	    Hereditary Hemolytic Anemias : 282
	    Organic Sleep Disorders : 327
	    Mononeuritis of Lower Limb and Unspecified Site : 355
	    Peritonitis and Retroperitoneal Infections : 567
	    Other Cellulitis and Abscess : 682
	    Other and Unspecified Congenital Anomalies : 759
	    Late Effects of Injuries to Skin and Subcutaneous Tissues : 906
	    Certain Early Complications of Trauma : 958
	    Complications Peculiar to Certain Specified Procedures : 996
	    Personal History of Other Diseases : V13
	    Organ or Tissue Replaced By Transplant : V42
	    Organ or Tissue Replaced By Other Means : V43
	    Other Postprocedural States : V45
	    Problems with Head, Neck, and Trunk : V48
	    Fitting and Adjustment of Other Device : V53
	    Convalescence and Palliative Care : V66
	    Follow-up Examination : V67
	    Special Screening Examination for Bacterial and Spirochetal Diseases : V74